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It is important that you tell your doctor about all the medicines you take including prescription and over-the-counter medicines, vitamins, and herbal supplements. Talk to your doctor about the best way to feed your baby if you take TIROSINT. Your doctor may need to change your TIROSINT dose while you are pregnant. TIROSINT is also not for use in people with temporary hypothyroidism caused by thyroiditis, or inflammation of the thyroid gland.ĭo not take TIROSINT if your adrenal glands are not working well and you have not been treated with glucocorticoid replacement for this problem.īefore you take TIROSINT, tell your healthcare provider about all your medical conditions, including if you: Currently have or have previously had heart problems currently have or have previously had thyroid nodules have kidney or pituitary gland problems have any food or drug allergies have a low red blood cell count have diabetes have weak or weakening bones (osteoporosis) currently have or have previously had a history of blood clotting problems.Īlso tell your healthcare provider if you are: Pregnant or planning to become pregnant, or are breastfeeding. TIROSINT should not be used by children less than 6 years of age or who cannot swallow an intact capsule. Over dosage or taking too much TIROSINT may cause life-threatening side effects or death. Do not take more TIROSINT than your doctor prescribes. Who need surgery and radioiodine therapy to manage a type of thyroid cancer called thyroid-dependent well-differentiated thyroid cancer.ĭo not use TIROSINT to treat weight problems or for weight loss.To replace or give extra levothyroxine in people whose thyroid gland does not naturally produce enough (a condition called hypothyroidism).It is used to treat adults and children 6 years of age and older: TIROSINT® (levothyroxine sodium) is a prescription medicine that contains a hormone called levothyroxine which is normally produced in your body by the thyroid gland. What is the most important information you should know about TIROSINT? Larger doses may produce serious or even life threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Thyroid hormones, including TIROSINT, either alone or with other therapeutic agents, should not be used for the treatment of obesity or for weight loss. NOT FOR TREATMENT OF OBESITY OR FOR WEIGHT LOSS IMPORTANT SAFETY INFORMATION for TIROSINT (levothyroxine sodium) CAPSULES EMPATHY: A new tool for identifying the most suitable thyroxine formulation in hypothyroid patients. Thyroxin softgel capsule in patients with gastric-related T4 malabsorption.

Based on RelayHealth eVoucherRx™ Network pharmacy paid claims from April 2018–March 2019.

Lugano, Switzerland: Institut Biochimique SA (IBSA) 2018. Herb and supplement use in the US adult population. When bioequivalence in healthy volunteers may not translate to bioequivalence in patients: differential effects of increased gastric pH on the pharmacokinetics of levothyroxine capsules and tablets.

Seng Yue S, Benvenga S, Scarsi C, Loprete L, Ducharme MP.

A comparative pH-dissolution profile study of selected commercial levothyroxine products using inductively coupled plasma mass spectrometry.

Data on file, Institut Biochimique SA (IBSA).

Comorbidities, concomitant medications, and diet as factors affecting levothyroxine therapy results of the CONTROL Surveillance Project.

McMillan M, Rotenberg KS, Vora K, et al.

The influence of lactose intolerance and other gastro-intestinal tract disorders on L-thyroxine absorption.

Ruchala M, Szczepanek-Parulska E, Zybek A.

Retrospective study of patients switched from tablet formulations to a gel cap formulation of levothyroxine: results of the CONTROL Switch Study.

Ernst FR, Sandulli W, Elmor R, Welstead J, Sterman AB, Lavan MK.

Lugano, Switzerand: Institut Biochimique SA (IBSA) 2018. Clinical Practice Guidelines for Hypothyroidism in Adults: Cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association.

ATA/AACE Taskforce on Hypothyroidism in Adults.Hypothyroidism: A Booklet for Patients and Their Families.